EMBOL-EI (Research Interest antiphospholipid antibody for embolic risk prediction in
infective endocarditis) is a prospective cohort study with a biological collection.
The main objective is: to re-evaluate the potential value of antiphospholipid (aPL)
antibodies as predictors of embolic events in IE in the light of the improved current
knowledge on these aPL.
The seconds objectives are: Other plasma biomarkers of hemostasis (coagulation activation
markers: D-dimer fragment 1 + 2 of prothrombin; endothelial biomarkers: plasma levels of von
Willebrand factor) will be taken into account in the analysis, and interest in predicting
embolic risk, alone or in combination with aPL will be investigated.