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More info
You can access this
clinical trial
if you have
Atrial Fibrillation
and you are
over 18
years old
The phase for this study is not defined.
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The purpose

The purpose of this study is to analyze the association of atrial fibrillation onset in normal heart and: - Genetic determinants (genes of receptors, enzymes involved in synthesis and degradation, genes of bioavailability of coenzymes and nutritional precursors) - Metabolic determinants of adenosine and methionine cycles - Nutritional determinants. Secondary purposes are: - Analysis of physiopathologic mechanisms of AF in normal hearts and adenosine metabolisms and its interaction with methionine metabolism, according to identified genetic determinants - Analysis of blood markers of adenosine and methionine metabolites as phenotypic markers of detected polymorphisms - Evaluate the role of adenosine receptors in AF onset

Provided treatments

  • Other: Quantification assay of adenosine and methionine cycle metabolites
  • Genetic: Polymorphism analysis of genes related to adenosine metabolism and methionine cycle
  • Other: Quantitative and qualitative nutritional evaluation
  • Biological: Blood sample

Locations near you

Unfortunately, there are no recruiting locations near you. Please check the list with all locations below.
Tris trial is registered with FDA with number: NCT02885740. The sponsor of the trial is Central Hospital, Nancy, France and it is looking for 400 volunteers for the current phase.
Official trial title:
Role and Interactions of Adenosine, Receptors, Methionine Cycle Nutritional, Metabolic and Genetic Determinants in the Onset of Atrial Fibrillation in Normal Heart