Improve knowledge of the immune response to sepsis in obese patients. Define immunological
and genetic prognostic factors of severe infections which can motivate a change in the
Biological: blood analysis
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Full eligibility criteria for NCT02882568
Ages eligible for Study
18 Years to 80 Years
Genders eligible for Study
Accepts Healthy Volunteers
between18 and 80 years
obesity: BMI > 30
presumed bacterial infection:
pneumonitis (documented or probably)
pyelonephritis / acute prostatitis
soft tissue / skin infection (except for bedsore)
cholecystitis / angiocholitis
surgical site infection
patients with viral, parasitic or mycotic documented infection
patients with bacterial infection with treatment> 4 weeks (ex. endocarditis; osteo- articular infections)
patients with prior antibiotic treatment (< 14 days)
intensive care unit patients
patients with a history of cancer or malignant hematological disease within the 5 previous years that is currently clinically significant (non metastatic prostatic and basocellular malignancy are excluded)
patients with systemic disease
Known diagnosis of human immunodeficiency infection (DICV, HIV…)
immunosuppression treatment during last month including corticotherapy
3 months follow up not possible
non signed consent
All locations for NCT02882568
Le Chesnay, France
View full eligibility
Tris trial is registered with FDA with number: NCT02882568. The sponsor of the trial is Versailles Hospital and it is looking for 15 volunteers for the current phase.
Official trial title: Analysis of Immune Response In Bacterial Infection of Obese Subject
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