The hypothesis is that the cough reflex induced by capsaicin is inhibited during exercise.
The purpose of this study is to determine if a short muscular exercise inhibits the cough
reflex induced by capsaicin inhalation.
Drug: Normal saline
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Full eligibility criteria for NCT02882555
Ages eligible for Study
7 Years to 77 Years
Genders eligible for Study
Accepts Healthy Volunteers
Obtaining of informed consent (or informed consent of parents or persons with parental authority)
Affiliation to social security
Negative answer to all 12 questions of medical questionnaire for child or to all 11 questions of medical questionnaire for adult
Normal cardio-respiratory examination
Without spirometry obstructive syndrome (FEV1 > 70% of predicted value and FEV1/FVC
Refusal or impossibility of obtaining informed consent of person or of persons with parental authority)
All locations for NCT02882555
View full eligibility
Tris trial is registered with FDA with number: NCT02882555. The sponsor of the trial is Central Hospital, Nancy, France and it is looking for 60 volunteers for the current phase.
Official trial title: Effect of Muscular Exercise on Cough Reflex
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