The goal of this study is to investigate the safety and tolerability of allogeneic Wharton's
jelly-derived mesenchymal stem cells administration in the individuals with diagnosed
amyotrophic lateral sclerosis.
Other: Biological: Cell-based therapy
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Full eligibility criteria for NCT02881476
Ages eligible for Study
18 Years to 65 Years
Genders eligible for Study
Accepts Healthy Volunteers
diagnosis of the ALS disease before the cell transplantation (diagnose established following the El Escorial criteria for definite ALS)
good understanding of the protocol and willingness to consent
signed informed consent
disease duration: up to 2 years
FVC > 50% / pulmonologist certificate about respiratory function of the patient
subject is a respiratory dependent.
subject unwilling or unable to comply with the requirements of the protocol
All locations for NCT02881476
View full eligibility
Tris trial is registered with FDA with number: NCT02881476. The sponsor of the trial is University of Warmia and Mazury and it is looking for 30 volunteers for the current phase.
Official trial title: Application of Wharton's Jelly-derived Mesenchymal Stem Cells in the Treatment of Amyotrophic Lateral Sclerosis
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