The primary scientific objective of the study entails examining whether altered endogenous
pain inhibition is present in children with functional abdominal pain (FAP) and irritable
bowel syndrome (IBS) compared with healthy controls (Part 1). A secondary objective implies
examining whether pediatric pain neuroscience education (PNE) is able to improve pain
catastrophizing, pain-related fear, pain intensity (including symptoms and indices of central
sensitization) and pain-related functional disability in children with FAP or IBS (Part 2).