Type 2 Diabetes (TD2) is the leading cause of new cases of preventable blindness in these
countries (and the gold-standard treatment, laser photocoagulation has proven to be effective
in preventing vision loss at the end stage of eye disease due to proliferative diabetic
retinopathy (PDR) that occurs in 3 to 6 % of the cases.Therefore, the ongoing search for
predictive factors of sight threatening stages of diabetic retinopathy has become more
Previous studies that have examined candidate predictive factors for diabetic eye disease
have mostly focused on systemic risk factors leading to PDR. Among various clinical
parameters, increased HbA1c % levels, uncontrolled blood pressure, diabetes duration,
neuropathy and elevated triglycerides have been associated with PDR.
Some genetic factors may also account for the development of PDR and are prospectively
considered in this study .