Stroke is frequently associated with significant disability and impaired quality of life.
Persistent motor impairment is common with often incomplete recovery of motor function in
response to rehabilitation, mainly in the upper limbs. Robot-mediated therapy has been
proposed as a viable approach for the rehabilitation of the upper limb, but as the evidence
quality is low, more rigorous studies are needed. Previous studies have focused on the
effects of devices acting on a limited number of joints, often limiting the workspace on a
plane. This study aims to evaluate the efficacy of a multi-set of robotic and technological
devices for the rehabilitation of the upper limb in sub-acute stroke patients.