Background: In women with hormone receptor positive (HR+) breast cancer, adjuvant endocrine
therapy (AET) is associated with a significant survival advantage. Nonadherence is a
particular challenge in older women, even though they stand to benefit the most from AET.
Therefore, a novel e-health tool (OPTIMUM) that integrates real-time analysis of health
administrative claims data was developed to provide point-of-care decision support for