Study the efficacy of endoresection of the tumor scar or, when surgery is not possible,
transpupillary thermotherapy on the tumor scar to prevent neovascular glaucoma and secondary
Procedure: Laser diode
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Full eligibility criteria for NCT02874040
Ages eligible for Study
18 Years and older
Genders eligible for Study
Accepts Healthy Volunteers
Tumor of 7 mm of thickness or more
Patients treated by proton beam therapy
Patients aged at least 18 years
Patients clearly informed of the study, having received the letter of information and signed the consent
Massive extrascleral extension posterior to the equator
Patients with metastasis at diagnosis.
Patients with glaucoma before the radiation therapy
Patients with opaque media preventing transpupillary thermotherapy
Patients for whom follow up will be difficult due to geographical, social or psychological reasons
All locations for NCT02874040
Paris, France, 75005
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Tris trial is registered with FDA with number: NCT02874040. The sponsor of the trial is Institut Curie and it is looking for 90 volunteers for the current phase.
Official trial title: Phase II Evaluating Endoresection of the Tumor Scar or Transpupillary Thermotherapy When Endoresection is Not Feasible After Proton Beam Therapy for the Treatment of Large Uveal Melanomas
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