Free fatty acid index will be measured in patients before and 1 month after high dose
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Full eligibility criteria for NCT02872584
Ages eligible for Study
18 Years and older
Genders eligible for Study
Accepts Healthy Volunteers
Each participant must be at least 18 years of age.
Each participant must give a written informed consent for participation in the study.
Each participant must be drug naïve with respect to previous glucocorticoid treatment
(history of less than 2-week treatment at any time is authorized, but with no recent glucocorticoid therapy over 3 months before study entry).
Obese subjects, defined as BMI > 35 or underweight subjects, defined as BMI < 18.5
A history of eating disorder
A history of Cushing's syndrome, subclinical hypercortisolism, hypoadrenalism, or congenital adrenal hyperplasia
Abnormal thyroid function test : history of hyperthyroidism or hypothyroidism
Uncontrolled hypertension >160/95
Hypercholesterolemia, defined as LDL > 190
Hypertriglyceridemia, defined as TG > 250
Acute or Chronic renal failure (GFR < 45) or nephrotic syndrome
Acute or chronic hepatitis or cirrhosis
All locations for NCT02872584
View full eligibility
Tris trial is registered with FDA with number: NCT02872584. The sponsor of the trial is Rambam Health Care Campus and it is looking for 20 volunteers for the current phase.
Official trial title: Serum Free Fatty Acids Desaturase Activity Indices in Sera of Patients on Long-term High-dose Corticosteroid Treatment
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