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More info
You can access this
clinical trial
if you have
Type 2 Diabetes Mellitus, Obese or Overweight
and you are
between 18 and 70
years old
2
This is a second phase trial assessing
efficacy and side effects of the new treatment.
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The purpose

To study the effect of an ileocolonic formulation of ox bile extract on insulin sensitivity, postprandial glycemia and incretin levels, gastric emptying, body weight and fasting serum FGF-19 (fibroblast growth factor) levels in overweight or obese type 2 diabetic subjects on therapy with DPP4 (dipeptidyl peptidase-4) inhibitors (e.g. sitagliptin) alone or in combination with metformin.

Provided treatments

  • Radiation: Gastric Emptying test
  • Other: Mixed Oral Glucose Tolerance test
  • Drug: Conjugated bile acids sodium
  • Other: Placebo

Locations near you

Unfortunately, there are no recruiting locations near you. Please check the list with all locations below.
Tris trial is registered with FDA with number: NCT02871882. The sponsor of the trial is Mayo Clinic and it is looking for 24 volunteers for the current phase.
Official trial title:
Effect of Delayed-Release Bile Acid on Insulin Sensitivity, Gastric Emptying and Body Weight in Overweight or Obese Patients With Type 2 Diabetes Mellitus