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Your journey
1What's a trial
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More info
You can access this
clinical trial
if you have
Type 2 Diabetes Mellitus, Obese or Overweight
and you are
between 18 and 70
years old
This is a second phase trial assessing
efficacy and side effects of the new treatment.
Show me locations

The purpose

To study the effect of an ileocolonic formulation of ox bile extract on insulin sensitivity, postprandial glycemia and incretin levels, gastric emptying, body weight and fasting serum FGF-19 (fibroblast growth factor) levels in overweight or obese type 2 diabetic subjects on therapy with DPP4 (dipeptidyl peptidase-4) inhibitors (e.g. sitagliptin) alone or in combination with metformin.

Provided treatments

  • Radiation: Gastric Emptying test
  • Other: Mixed Oral Glucose Tolerance test
  • Drug: Conjugated bile acids sodium
  • Other: Placebo

Locations near you

Unfortunately, there are no recruiting locations near you. Please check the list with all locations below.
Tris trial is registered with FDA with number: NCT02871882. The sponsor of the trial is Mayo Clinic and it is looking for 24 volunteers for the current phase.
Official trial title:
Effect of Delayed-Release Bile Acid on Insulin Sensitivity, Gastric Emptying and Body Weight in Overweight or Obese Patients With Type 2 Diabetes Mellitus