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More info
You can access this
clinical trial
if you have
Dental Erosion
and you are
between 20 and 40
years old
-
This is an observational trial.
You are contributing to medical knowledge about your condition.
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The purpose

Healthy volunteers are observationally wearing an intraoral device with bovine tooth samples once for two hours. Afterwards, Calcium release from the bovine enamel and dentin samples is measured after extraoral erosion. Total protein concentration within the formed salivary pellicles on the bovine samples is determined. Further Salivary parameters (unstimulated and stimulated saliva flow rate, pH, buffer capacity, albumin and total protein content as well as concentration of inorganic calcium, phosphate and fluoride) are being measured. The aim of this study is to investigate whether gender differences in the salivary composition correlate with predisposition to erosion.

Provided treatments

  • Other: Wearing of an intraoral device with bovine tooth samples
Tris trial is registered with FDA with number: NCT02780973. The sponsor of the trial is University of Göttingen and it is looking for 50 volunteers for the current phase.
Official trial title:
Influence of Gender Specific Differences of Saliva Composition on the Development of Dental Erosion - an In-situ Study