Brazilian National Cancer Institute
Cancer cachexia is a complex metabolic process affecting up to 80% of patients suffering from an advanced-stage cancer. Moreover, 20 to 40% of all cancer deaths are caused directly by cachexia. Recently, omega-3 fatty acids have gained interest for their beneficial effects in cancer cachexia. Moreover, nutritional supplementation enriched with omega-3 could potentially maintain body weight in cancer patients undergoing intensive treatment. The investigators aims in this study is to evaluate the effect of omega-3 supplementation on body composition, functional capacity, inflammatory profile and quality of life in cervix cancer patients undergoing chemoradiotherapy.
- : Omega-3patients included in this group will take 2g (4 capsules) per day of eicosapentaenoic acid.
- intervention group
- : Olive oilpatients included in this group will take 4 capsules per day of olive oil.
- placebo group
|Ages eligible for Study||20 Years to 59 Years|
|Genders eligible for Study||Female|
|Accepts Healthy Volunteers||No|
- Cervix cancer at FIGO stage II and III
- Chemoradiotherapy treatment proposal (cisplatin + radiotherapy)
- Nutritional diagnosis of pre-cachexia ou cachexia
- metastasis (FIGO stage IV)
- Nutritional diagnosis of refractary cachexia
- Brazilian National Cancer InstituteNot specifiedRio de Janeiro, RJ, Brazil, 20220-410
30 April, 2016
23 July, 2017