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Your journey
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More info
You can access this
clinical trial
if you have
Healthy Volunteer or HIV Vaccine
and you are
between 18 and 49
years old
1
This is an early phase trial to determine
the dosage and safety of the new treatment.
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The purpose

The purpose of this study is to test experimental human immunodeficiency virus (HIV) vaccines that use an adenovirus vector. The adenovirus vector may help the vaccines stimulate an immune response. Researchers want to see how the immune system will respond to these vaccines as well as if they are safe to give to people. Participants cannot get HIV from these vaccines. However, researchers also want to see if the vaccine's adenovirus is contagious. Adenoviruses cause cold symptoms or mild eye infections, therefore household and intimate contacts will be asked to participate as well.

Provided treatments

  • Biological: Ad4-mgag
  • Biological: Ad4-EnvC150
  • Other: Placebo Comparator
  • Biological: AIDSVAX B/E
Tris trial is registered with FDA with number: NCT02771730. The sponsor of the trial is PaxVax, Inc. and it is looking for 60 volunteers for the current phase.
Official trial title:
A Phase 1 Clinical Trial to Evaluate the Safety and Immunogenicity of Orally-administered Replication-competent Adenovirus Type-4 HIV Vaccine Regimens in Combination With an AIDSVAX® B/E Boost in Healthy, HIV-uninfected Adult Participants