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More info
You can access this
clinical trial
if you have
Fever
and you are
over 1
years old
-
The phase for this study is not defined.
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The purpose

PRIMARY OBJECTIVE To assess the impact of C-reactive protein (CRP) Point-of-care (POC) testing on health care worker prescribing behaviour in patients presenting to primary healthcare centres with an acute fever or recent history of fever. SECONDARY OBJECTIVES To assess the impact of CRP testing on clinical outcomes within the 14 days of follow-up. To assess the correlation between CRP results and clinical outcomes on the day 5 of the enrolment. To estimate the impact of CRP testing on antibiotic consumption after first consultation. To explore the attitudes of health centre staff towards the POC CRP test. To identify the prevalence of key pathogens in febrile patients in these settings. To validate the ability of CRP to discriminate between viral and bacterial pathogens in a subset of patients with a microbiologically confirmed diagnosis.

Provided treatments

  • Other: No CRP will be measured onsite
  • Other: CRP cut-off of 20mg/L.
  • Other: CRP cut-off of 40mg/L.
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Tris trial is registered with FDA with number: NCT02758821. The sponsor of the trial is University of Oxford and it is looking for 2400 volunteers for the current phase.
Official trial title:
The Impact of C-reactive Protein Testing on Antibiotic Prescription in Febrile Patients Attending Primary Care in Low-resource Settings