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More info
You can access this
clinical trial
if you have
Acute Respiratory Failure or Pneumonia
and you are
between 20 and 85
years old
-
The phase for this study is not defined.
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The purpose

BACKGROUND: Endotracheal intubation and prolonged immobilization of patients receiving mechanical ventilation may reduce expectoration function. High frequency chest wall oscillation (HFCWO) may ameliorate airway secretion movement; however, the vigorous oscillation may influence ventilator settings and change instantaneous cardiopulmonary responses. The aim of this study was to investigate these issues. METHODS: Seventy-three patients aged >20 years who were intubated with mechanical ventilation for pneumonic respiratory failure were recruited and randomly classified into two groups (HFCWO group, n=36; and control group who received conventional chest physical therapy (CCPT), n=37). HFCWO was applied with a fixed protocol, while CCPT was conducted using standard protocols. Both groups received sputum suction after the procedure. Changes in ventilator settings and the subjects' responses were measured at pre-set intervals and compared within groups and between groups.

Provided treatments

  • Device: Vest Airway Clearance System Model 105
  • Device: placebo intervention
Tris trial is registered with FDA with number: NCT02758106. The sponsor of the trial is Chung Shan Medical University and it is looking for 73 volunteers for the current phase.
Official trial title:
The Instantaneous Effects of High-Frequency Chest Wall Oscillation on Patients With Acute Pneumonic Respiratory Failure Receiving Mechanical Ventilation