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(NCT02756975)

Prostate tissue biopsy is performed with either transrectal or transperineal approach. These two methods are usually based on tissue sampling with an ultrasound-guided core needle biopsy. Transperineal prostate biopsy can be done either with a conventional noncoaxial technique or with a coaxial technique. In conventional transperineal technique, biopsy needle is inserted repeatedly for each tissue sampling. Alternatively, a coaxial needle can be placed over the perineum; then, the direction of the biopsy can be changed by tilting the coaxial needle. In this prospective study, the investigators sought to compare the procedural time and the complication rate of coaxial technique with those of noncoaxial technique in transperineal prostate biopsy.
  • Device: coaxial prostate biopsy
    In this method, a larger introducing needle is needed for the puncture. The introducing needle is placed over the perineum. The biopsy needle is inserted throughout the introducing needle.Then, the direction of the biopsy is changed by tilting the coaxial needle. The investigator needs to puncture the prostate capsule only once for sampling at each each side of the prostate (right and left sides).
    • coaxial Tru-Cut needle (18-gauge Bard Max-Core Disposable Core Biopsy Instrument, 17-gauge Bard TruGuide Disposable Coaxial Needle; C. R. Bard, Tempe, USA)
  • Device: noncoaxial prostate biopsy
    In this method, there is no introducing needle. Biopsy needle is inserted repeatedly for each tissue sampling (at least fourteen times). A smaller biopsy needle is used for the puncture in this method. The main disadvantage of the coaxial technique is that a larger introducing needle is needed for the puncture (12). On the other whand, the advantage of noncoaxial method is that the needle is within the prostate for only a few seconds to document needle position with ultrasonography before firing
    • noncoaxial 18-gauge needle (Bard Max-Core Disposable Core Biopsy Instrument; C. R. Bard, Tempe, USA)
Ages eligible for Study
20 Years to 90 Years
Genders eligible for Study
Male
Accepts Healthy Volunteers
No
Inclusion Criteria:
  • an elevated prostate-specific antigen (PSA) level
  • suspicious digital rectal examination
Exclusion Criteria:
  • a history of prostate cancer
  • clinical findings of acute or chronic prostate inflammation
  • a history of urogenital procedures

1 locations

Iran, Islamic Republic of (1)
  • Department of Radiology, Poursina Hospital, Guilan University of Medical Sciences
    Not specified
    Rasht, Guilan, Iran, Islamic Republic of
Status:
unknown
Type:
Interventional
Phase:
-
Start:
30 November, 2014
Updated:
26 April, 2016
Participants:
240
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