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Your journey
1What's a trial
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3Review
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More info
You can access this
clinical trial
if you have
Nasopharyngeal Carcinoma
and you are
between 18 and 65
years old
3
This is a trial in the final phase before the treatment is released on the market.
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The purpose

Currently, most protocols of nasopharyngeal carcinoma(NPC) of various research bodies such as the Radiation Therapy Oncology Group require routine elective irradiation to the retropharyngeal area and to levels II-V, and also to the supraclavicular lymph nodal areas regardless of the status of nodal metastasis. Previous studies had confirmed that the pattern of cervical lymph node metastasis in NPC followed an orderly manner. Retropharyngeal lymph nodes (RLNs) and Level II LNs were the most commonly involved, followed by Level III and Level V LNs, Level IV LNs, and SCF LNs, and the incidence of LN skip metastasis is rare, ranging from 0.5% to 7.9%. It was rare for NPC patients without neck lymph node metastases to experience neck failure after elective irradiation to levels II, III and VA. It also confirmed that with unilateral LN metastases of higher-level LNs usually spread down ipsilateral LNs.Thus, the investigators conduct the non-inferior randomized trial to determine the value of elective neck irradiation in NPC with N0-N1.

Provided treatments

  • Radiation: Elective neck irradiation
  • Radiation: Whole neck irradiation

Locations near you

Unfortunately, there are no recruiting locations near you. Please check the list with all locations below.
Tris trial is registered with FDA with number: NCT02642107. The sponsor of the trial is Sun Yat-sen University and it is looking for 446 volunteers for the current phase.
Official trial title:
The Multicenter Randomized Phase 3 Trial of Individualized Elective Neck Irradiation Based on MRI in Patients With Nasopharyngeal Carcinoma