Primary Objective: This study will evaluate the effectiveness of an HCV Care Facilitation
intervention in moving HIV/HCV co-infected substance users forward along the HCV care
continuum (compared with a Control group).
Primary Hypothesis: The number of steps achieved along the HCV care continuum will differ
between the two study groups over the 14-month follow-up period.
Component 1 (Long-term CTN 0049 follow-up):
Using the CTN 0064 baseline data (self-report, medical record abstraction and biological
data), the following CTN 0049 primary and secondary outcomes in participants who consented to
the CTN 0064 protocol will be re-analyzed to evaluate latent and/or enduring effects of the
CTN 0049 interventions:
1. HIV virological suppression
2. HIV primary care visit attendance
3. All-cause mortality