BACKGROUND: Studies have shown that COPD patients with bronchial hypersecretion have
increased risk of acute exacerbations. FREE ASPIRE is an electro-medical device which removes
bronchopulmonary secretions noninvasively, without using a suction catheter and without
generating airway pressure.
AIM: To compare FREE ASPIRE activity with the traditional treatment using PEP-bottle in the
clearance of bronchial secretions in COPD patients METHODS: Forty severe and very severe COPD
patients with mucus and reduced cough will be evaluated. Group comparison will be made
between Intervention group using VAKÜM system (Free Aspire®), and Control group using
traditional treatment with PEP-bottle over 10 daily sessions (20 minutes twice a day).
Primary outcomes are changes in arterial blood gases exchanges, in perceived dyspnea and in
symptom of bronchial encumbrance.
EXPECTED RESULTS: A higher significant reduction of the perceived dyspnea and of perceived
bronchial encumbrance is supposed in the Intervention group. Additional benefits among the
secondary outcomes are also hypothesized in the same group.