IDA patients ofen receive ferrous succinate treatment to speed up the recovery of anemia, the
doctor will prescribe ferrous succinate with or without vitamin C according to their own
preferences. In theory, only the divalent iron can be absorbed in duodenum and upper jejunum,
vitamin C can oxidize ferric iron into divalent iron and maintains a certain degree of
acidity in the intestine, and then promotes the absorption of iron. In current clinical
practice, it's lack of randomized controlled trial(RCT) about the efficacy and safety of
vitamin C for iron supplementation in patients with IDA. In this study, the efficacy and
safety of vitamin C for iron supplementation in adult IDA patients are explored by RCT. The
dosage regimens of ferrous succinate with or without vitamin C are randomly assigned to
patients who meet the inclusion criteria, and these patients are followed up every two weeks.
On the one hand, whether the addition of vitamin C can accelerate the recovery of anemia is
evaluated, on the other hand, whether the addition of vitamin C can increase the incidence of
gastrointestinal tract discomfort is aslo appraised , the discomfort include vomiting,
nausea, abdominal pain, diarrhea and constipation. We hypothesis that vitamin C can increase
the absorption of iron and accelerate the recovery of anemia, it also increases incidence of
gastrointestinal adverse events because of increased iron absorption at the same time.