To investigate the effects of methylphenidate on motivated behavior in adults with and
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Full eligibility criteria for NCT02630017
Ages eligible for Study
18 Years to 45 Years
Genders eligible for Study
Accepts Healthy Volunteers
between the ages of 18-45
non-ADHD subjects do not meet criteria for ADHD diagnosis or any subtype as determined by the Conners Diagnostic Interview or any T-Score > 55 on Inattentive Symptoms, Hyperactive-Impulsive Symptoms, Total Symptoms or ADHD Index subscales of the CAARS.
ADHD subjects meet criteria for a primary diagnosis of ADHD, any subtype, based on DSM-5
inability to attend all required experimental sessions
significant health problems (e.g., current and uncontrolled liver, lung, or heart problems, current or past seizure disorder, serious head trauma)
primary diagnosis of Axis I psychiatric disorders other than ADHD (e.g., depression, anxiety disorder, schizophrenia)
meet DSM-5 criteria for substance use disorder other than nicotine in the past 12 months
use of psychoactive medications in the past 6 months as indicated by self-report
positive urine drug screen for drugs or positive breath alcohol concentration
contraindications for MPH
among women, nursing or a positive pregnancy test
IQ < 80 on Kaufman Brief Intelligence Test, 2nd edition
allergy to lactose
hypertension (If subject is ≤ 40 years of age and has blood pressure over 135/85 or heart rate over 90 beats per minute. If subject is > 40 years of age and has blood pressure over 130/80 or heart rate over 88 beats per minute)
body mass ratio > 30
All locations for NCT02630017
United States (1)
University of Arkansas for Medical Sciences
Little Rock, Arkansas, United States, 72227
View full eligibility
Tris trial is registered with FDA with number: NCT02630017. The sponsor of the trial is University of Arkansas and it is looking for 30 volunteers for the current phase.
Official trial title: Motivated Behavior in Adults With and Without ADHD
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