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More info
You can access this
clinical trial
if you have
Chronic Kidney Disease
and you are
between 18 and 100
years old
3
This is a trial in the final phase before the treatment is released on the market.
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The purpose

This research study is designed to assess the safety and effectiveness of an experimental drug called vonapanitase (PRT-201) in patients both receiving or expecting to receive hemodialysis who have chronic kidney disease and who are undergoing surgery to create a new access point to their bloodstream for hemodialysis. Vonapanitase is a protein that has been shown in previous research studies to help keep vessels patent when applied to the outside surface of the blood vessels (arteries and veins) in patients who undergo surgery to create an arteriovenous fistula (AVF). The purpose of this study is to determine whether vonapanitase when applied to a limited segment of your blood vessel (about 2 inches) immediately after surgery is safe and improves the patency of your AVF.

Provided treatments

  • Drug: vonapanitase
  • Drug: Placebo
Tris trial is registered with FDA with number: NCT02414841. The sponsor of the trial is Proteon Therapeutics and it is looking for 600 volunteers for the current phase.
Official trial title:
Multicenter, Double Blind, Placebo Controlled Study of Vonapanitase (PRT- 201) Administered Immediately After Radiocephalic Arteriovenous Fistula Creation in Patients With Chronic Kidney Disease