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More info
You can access this
clinical trial
if you have
Type 2 Diabetes Mellitus
and you are
between 18 and 65
years old
1
This is an early phase trial to determine
the dosage and safety of the new treatment.
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The purpose

This study will evaluate the absolute oral bioavailability (F) and fraction absorbed (Fa) of ertugliflozin following oral administration of unlabeled ertugliflozin (MK-8835) and intravenous (IV) and oral administration of 14^C-labeled ertugliflozin in healthy male participants.

Provided treatments

  • Drug: Unlabeled ertugliflozin for oral use
  • Drug: 14^C-labeled ertugliflozin for IV use
  • Drug: 14^C-labeled ertugliflozin for oral use
Tris trial is registered with FDA with number: NCT02411929. The sponsor of the trial is Merck Sharp & Dohme Corp. and it is looking for 8 volunteers for the current phase.
Official trial title:
A Phase 1, Open-Label, Non-Randomized, 2-Period, Fixed Sequence, Study to Assess the Absolute Bioavailability and Fraction Absorbed of Ertugliflozin in Health Male Subjects Using a 14^C-Microdose Approach