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You can access this
clinical trial
if you have
Non-small Cell Lung Cancer (NSCLC)
and you are
over 18
years old
1
2
This is a medium phase trial determining
the safety and dosage of the new treatment, as well as its efficacy.
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The purpose

The purpose of this study is to determine the safety, tolerability, feasibility and preliminary efficacy of the administration of PBF-509 (Adenosine A2a receptor antagonist) as single agent or in combination with PDR001 (programmed cell death 1 receptor antibody (PD-1 Ab)) to NSCLC patients.

Provided treatments

  • Drug: PBF-509_80 mg
  • Drug: PBF-509_160 mg
  • Drug: PBF-509_320 mg
  • Drug: PBF-509_640 mg
  • Drug: Combo PBF-509 (160 mg) + PDR001
  • Drug: Combo PBF-509 (320 mg) + PDR001
  • Drug: Combo PBF-509 (640 mg) + PDR001
  • Drug: RP2D (PBF-509+PDR001)_immuno naïve
  • Drug: Experimental: RP2D (PBF-509+PDR001)_immuno treated
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Locations near you

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Tris trial is registered with FDA with number: NCT02403193. The sponsor of the trial is Palobiofarma SL and it is looking for 92 volunteers for the current phase.
Official trial title:
Phase I/Ib Trial of Single Agent PBF-509 and in Combination With PDR001 for Patients With Advanced NSCLC