The main purpose of this study is to determine whether dietary nitrate supplementation via
concentrated beetroot juice improves central and peripheral cardiovascular control and
physical capacity in patients with systolic heart failure.
: Nitrate supplementation
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Full eligibility criteria for NCT02401126
Ages eligible for Study
40 Years to 80 Years
Genders eligible for Study
Accepts Healthy Volunteers
previous diagnosis of systolic heart failure (left ventricular ejection fraction <40%) under optimized clinical treatment as judged by the accompanying physician.
hospital admission in the previous 6 weeks;
exercise training program in the previous 6 months;
nitrate therapy (e.g., isosorbide dinitrate);
any condition that could interfere with the ability to exercise;
Tris trial is registered with FDA with number: NCT02401126. The sponsor of the trial is Queen's University and it is looking for 13 volunteers for the current phase.
Official trial title: Dietary Nitrate Supplementation and Cardiorespiratory Control in Chronic Heart Failure: a Randomized, Placebo-controlled Trial
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