There is accumulating evidence that genetic expression plays a role in autism spectrum
disorder, but the regulation of such genes is poorly understood. Small RNA particles, called
microRNA (miRNA), have the ability to alter gene expression. These particles can be packaged
and released from brain cells into the blood. Changes in miRNA may contribute to the patterns
observed in autism spectrum disorder.
The purpose of this study is to identify small RNA particles that regulate gene expression in
autism spectrum disorder. The goal is to identify miRNA expression patterns which may improve
our understanding and diagnosis of autism spectrum disorder.