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More info
You can access this
clinical trial
if you have
and you are
between 18 and 70
years old
The primary goal of this phase is to monitor the long-term effects.
The treatment is already on the market.
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The purpose

Low total testosterone (TT) is present in about 30% of men aged >60 years and in up to 7% of younger men. Male hypogonadism is associated with metabolic and cardiovascular diseases as well as with increased mortality. There is evidence showing a relationship of TT with vitamin D in men. We aim at evaluating the effect of vitamin D supplementation on TT and metabolic parameters in hypogonadal men. We will study the effects of 20,000 IU vitamin D weekly in a 12 wk randomized, double-blind, placebo-controlled trial in 100 men with TT <3.0 ng/ml and 25-hydroxyvitamin D (25(OH)D) <30 ng/ml (patients) as well as in 100 men with TT ≥3.0 ng/ml and 25(OH)D <30 ng/ml (controls). Vitamin D supplementation might be a safe therapeutic approach improving TT levels as well as metabolic parameters in hypogonadal men. Further the effects of vitamin D on androgens will be evaluated in eugonadal men.

Provided treatments

  • Drug: Vitamin D supplementation in hypogonadal men
  • Drug: Vitamin D supplementation in eugonadal men
  • Drug: Placebo hypogonadal
  • Drug: Placebo eugonadal

Locations near you

Unfortunately, there are no recruiting locations near you. Please check the list with all locations below.
Tris trial is registered with FDA with number: NCT01748370. The sponsor of the trial is Medical University of Graz and it is looking for 200 volunteers for the current phase.
Official trial title:
A Randomized, Double-blind, Placebo Controlled Trial to Evaluate the Effects of Vitamin D Supplementation on Androgen Levels in Hypogonadal Men