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You can access this
clinical trial
if you have
Healthy
and you are
over 18
years old
3
This is a trial in the final phase before the treatment is released on the market.
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The purpose

Long term treatment with anti-glaucomatous drugs has been shown to increase the incidence of dry eye syndrome with all known consequences such as ocular discomfort and epithelial keratitis. Given that thinning of the tear film appears to be a risk factor for the development or the aggravation of dry eye syndrome, the current study seeks to investigate whether tear film thickness is changed after topical treatment with anti-glaucomatous drugs in healthy subjects. For this purpose, tear film thickness will be measured at baseline and after single instillation of one of 5 study drugs in one randomly chosen eye. In addition, one group of 20 subjects will receive no drug and will serve as a second control. Drug effects on tear film thickness will be compared to the fellow, non-treated eye. In addition, effects on tear film thickness of timolol with preservatives (Timoptic 0.5%) will be compared to timolol without preservatives (Timophtal sine 0.5%) and three lubricants with different viscosity (Genteal HA, Hylo-Comod, Thealoz).

Provided treatments

  • Drug: Timoptic® 0.5%
  • Drug: Timophtal sine® 0.5%
  • Device: Genteal HA®
  • Device: Hylo-Comod®
  • Device: Thealoz®

Locations near you

Unfortunately, there are no recruiting locations near you. Please check the list with all locations below.
Tris trial is registered with FDA with number: NCT01746602. The sponsor of the trial is Medical University of Vienna and it is looking for 38 volunteers for the current phase.
Official trial title:
Effect of Topical Glaucoma Therapy on Tear Film Stability in Healthy Subjects