The goal of this clinical research study is to compare armodafinil and minocycline when given
alone or in combination to learn which is better for controlling side effects of
chemoradiation treatment for esophageal cancer (such as fatigue, pain, disturbed sleep, lack
of appetite, and drowsiness).
Armodafinil is designed to prevent excessive sleepiness.
Minocycline is an antibiotic, which may help to reduce multiple symptoms.
In this study, you may receive a placebo. A placebo is not a drug. It looks like the study
drug but is not designed to treat any disease or illness. It is designed to be compared with
a study drug to learn if the study drug has any real effect.