Overall goal of this study is to scrutinize the relation of learning behavior and related
brain activity to the development of alcohol use disorder (AUD).
The researchers aim is to characterise a representative sample (200 men at age 18) with
regard to learning parameters and their respective neural correlates which are thought to be
indicators for the risk to develop an alcohol use disorder.
As part of a large multi-center study on alcohol dependency (in Dresden & Berlin, Germany)
the researchers will characterize the sample and then prospectively assess alcohol
consumption and development of AUDs over a period of three years.
Among other hypotheses it is expected that increased activation of striatal and prefrontal
brain regions by the Pavlovian-to-instrumental transfer process is related to increased risk
of developing an AUD.