Introduction : Spine surgery is responsible for intense postoperative pain that can be
treated by an analgesia multimodal approach (IV analgesic infusion and local anesthesia).
Continuous wound infiltration is an efficient and simple technique with few adverse effects
yet very few studies have investigated its potential use in spine surgery. Our randomised,
controlled, double-blinded trial aims to evaluate efficacy of continuous wound infiltration
after major spine surgery.
Methods : After written consent is obtained, the surgeon inserts, at the end of surgery, a
multiholes catheter under muscular layers. Patients are randomised in two groups : The
"treated group" receives ropivacaine 0.2% infusion (bolus of 10 milliliters (mL) followed by
8 mL/h continuous infusion during 48 hours) and the "control group" receives saline solution
(0.9%). In addition, all patients receive patient-controlled intra-venous morphine analgesia.
The investigators hypothesize that the "treated group" will consume morphine less than the