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More info
You can access this
clinical trial
if you have
and you are
between 18 and 45
years old
This is an early phase trial to determine
the dosage and safety of the new treatment.
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The purpose

The purpose of this study is to determine how multiple doses of canagliflozin (JNJ-28431754) affect the pharmacokinetics (ie, how the body affects the drug) and pharmacodynamics (ie, how the drug affects the body) of a single dose of glyburide.

Provided treatments

  • Drug: Glyburide
  • Drug: Canagliflozin (JNJ-28431754)
Tris trial is registered with FDA with number: NCT01733108. The sponsor of the trial is Johnson & Johnson Pharmaceutical Research & Development, L.L.C. and it is looking for 29 volunteers for the current phase.
Official trial title:
An Open-Label Drug-Drug Interaction Study in Healthy Subjects to Explore the Effects of Multiple Doses of JNJ-28431754 on the Pharmacokinetics and Safety of Single Doses of Glyburide