Your journey
1What's a trial
4Get in touch
More info
You can access this
clinical trial
if you have
Blood Loss, Surgical
and you are
between 18 and 75
years old
This is an early phase trial to determine
the dosage and safety of the new treatment.
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The purpose

The standard of care for treatment of burn injury is to inject a solution of epinephrine under the skin of the injured site in order to reduce blood loss during skin grafting. This solution of epinephrine has been shown to have effects on the body outside the donor site. Some people have increases in heart rate and blood pressure. We will study the effect of a phenylephrine solution in place of an epinephrine solution to control blood loss. We think that phenylephrine will help decrease blood loss and not change blood pressure or heart rate. The injured area will be injected under the skin and a skin graft will be taken in the same way as we usually do. The only change will be the use of phenylephrine in the solution instead of epinephrine. Our goal is to find whether or not phenylephrine or epinephrine solution results in a reduction of blood loss without affecting the rest of the body.

Provided treatments

  • Drug: Phenylephrine
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Locations near you

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Tris trial is registered with FDA with number: NCT01731444. The sponsor of the trial is University of Manitoba and it is looking for 24 volunteers for the current phase.
Official trial title:
Phenylephrine Tumescence for Hemostasis in Surgery for Burn Injury - A Randomized Control Trial