Patients with acute migraine attack make up the majority of patients consulting the emergency
services due to headache. The aim of treatment in the emergency service is to achieve a
minimum level of undesirable side effects and to quickly relieve the pain which will not
repeat after discharge from the emergency service. Ideal drug treatment contraindication
should be at a minimum level and not trigger migraine. Paracetamol and Nonsteroidal
anti-inflammatory drugs are often used in the treatment of migraine headache.
Although narcotic analgesics provide effective and rapid analgesia, they have such side
effects as hypotension, nausea and vomiting, drowsiness. In recent years, with the production
of parenteral forms of non-steroidal anti-inflammatory painkillers, the analgesic efficacy of
these drugs has been one of the topics of interest to researchers. Especially intravenous
form of paracetamol is new yet compared to other Nonsteroidal anti-inflammatory drugs, and it
is a drug with a wide safety margin and less incidence of side effects. The effectiveness of
the Intravenous form of paracetamol and whether it can be an alternative to other analgesics
is one of the major research topics today, and more study is needed on this subject.
Both drugs are often used in emergency services to treat headache caused by acute migraine
attack. Our aim is to compare the effectiveness of intravenous dexketoprofen with paracetamol
in the treatment of the headache caused by acute migraine attack.