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Your journey
1What's a trial
2Find
3Review
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More info
You can access this
clinical trial
if you have
Newly Diagnosed High-Grade Glioma
and you are
over 18
years old
1
This is an early phase trial to determine
the dosage and safety of the new treatment.
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The purpose

The purpose of this study is to find the highest dose of mebendazole (MBZ) that can be safely given to people with malignant brain tumors in combination with the current standard of care (temozolomide) without causing severe side effects. We also want to find out if MBZ can slow the growth of the brain tumor. The study doctors have found that MBZ is effective against malignant brain tumors in the laboratory and animal models of brain tumors.

Provided treatments

  • Drug: Mebendazole

Locations near you

Unfortunately, there are no recruiting locations near you. Please check the list with all locations below.
Tris trial is registered with FDA with number: NCT01729260. The sponsor of the trial is Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins and it is looking for 24 volunteers for the current phase.
Official trial title:
Phase I Study of Mebendazole in Newly Diagnosed High-Grade Glioma Patients Receiving Temozolomide