This trial is terminated!
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You can access this
clinical trial
if you have
HIV Infection or Malaria
and you are
between 3 and 12
years old
Phase
4
The primary goal of this phase is to monitor the long-term effects.
The treatment is already on the market.
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The purpose

The purpose of this study is to see if taking nevirapine (NVP) for HIV changes the way artemether/lumefantrine (AL) works in children who are co-infected with both HIV and malaria. The brand of AL used in this study is Coartem® Dispersible. This study will compare the blood levels of AL in co-infected children who already take NVP prescribed by their doctor with the co-infected children who do not take anti HIV medicines because they do not meet national guidelines to start them. The study will also assess the safety of using both medications (AL and NVP) in children.

Provided treatments

  • Drug: Artemether/Lumefantrine (AL)
Tris trial is registered with FDA with number: NCT01728961. The sponsor of the trial is International Maternal Pediatric Adolescent AIDS Clinical Trials Group and it is looking for 19 volunteers for the current phase.
Official trial title:
Pharmacology of Artemisinin-Based Antimalarial Therapy Within the Context of Antiretroviral Therapy