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You can access this
clinical trial
if you have
Immune Thrombocytopenia
and you are
-
This is an observational trial.
You are contributing to medical knowledge about your condition.
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The purpose

Introduction: Ineffective platelet production has been proven to play a role in the etiology of Immune Thrombocytopenia (ITP) in addition to increased platelet destruction. The second-generation thrombopoietin (TPO) mimetics have shown good efficacy in boosting platelet counts in the great majority of patients with chronic ITP in several clinical trials.1, 2 Nevertheless, about 20% of patients with ITP fail to respond to the TPO mimetic treatment. Those treatment-resistant patients are un-characterized and the reasons for the lack of response have not been studied. The identification of predictive blood biomarkers of patients' response to treatment will be useful in reducing both cost and potential side effects; and it will be of equal importance and interest to investigate the molecular mechanisms underlying the patients' heterogeneous responses to TPO mimetic treatment. Specific Aims: 1. To identify blood classifier genes which correlate with patients' response to TPO mimetic treatment. 2. To compare the blood gene expression changes in responders and non-responders after TPO mimetic treatment and explore the possible molecular mechanisms accounting for the non-responsiveness to the treatment.

Locations near you

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Tris trial is registered with FDA with number: NCT01727999. The sponsor of the trial is Stanford University and it is looking for 75 volunteers for the current phase.
Official trial title:
Genome-Wide Gene Expression Profiling of Patients With ITP Receiving Thrombopoietin Mimetics