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The purpose

Current research on sperm morphology has been directed towards the dysmorphisms of the sperm head. A new technique based on the motile sperm organelle morphology examination (MSOME) allows the detection of sperm with large nuclear vacuoles (SLV). Large nuclear vacuoles are specific sperm alterations observed under high magnification, and their presence has been related to increased DNA fragmentation and denaturation.

Provided treatments

  • Other: MSOME

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Tris trial is registered with FDA with number: NCT01727947. The sponsor of the trial is Sapientiae Institute and it is looking for 200 volunteers for the current phase.
Official trial title:
Influence of Sperm With Large Nuclear Vacuoles on the Cycles' Outcomes of Couples Couples Undergoing ICSI