This pilot study is aimed at assessing the acute effect of several combinations of lipids
differing in their fatty acid composition on glucagon-like-peptide (GLP)-2 and GLP-1
secretion in healthy subjects.
: meal intake
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Locations near you
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Full eligibility criteria for NCT01727583
Ages eligible for Study
20 Years to 40 Years
Genders eligible for Study
Accepts Healthy Volunteers
BMI : 19 - 24.9 kg.m-2
Normal fasting glycemia
Having obtained his informed consent.
Gastro-intestinal disease (ulcer), pancreatic disease, hepatic disease, metabolic diseases / disorders (diabetes, dyslipidemia), renal disease, cardiovascular disease
(arterial hypertension), as determined by the medical screening visit and a blood analysis.
Have had a gastrointestinal surgery (with the exception of appendices resection).
Significant weight loss during the past three months (more than 5% of initial weight)
Have a regular consumption of medication
Regular supplements (vitamins and minerals) intake during the previous month
Have an alcohol intake: > 2 units a day
Smoker (more than 2 cigarettes a day)
Illicit substances intake, as stated on the medical screening questionnaire
Allergy to any food or medication
Anaemia defined by a number of erythrocytes or hemoglobin Hb or hematocrit Ht which are inferior to laboratory normal ranges
Having given blood in the past three months or willing to give blood in the 3 months following the completion of the study
Intense physical activity > 3 hours per week
Currently participating or having participated in another clinical trial during the past month.
Volunteer who cannot be expected to comply with the protocol, including consuming rapidly the study products, chronic medication intake
All locations for NCT01727583
Nestlé CDU / Metabolic Unit
Lausanne, Switzerland, 1000
View full eligibility
Tris trial is registered with FDA with number: NCT01727583. The sponsor of the trial is Nestlé and it is looking for 18 volunteers for the current phase.
Official trial title: Boosting the Secretion of GLP-2 and GLP-1 Intestinal Hormones by Nutrients
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