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More info
You can access this
clinical trial
if you have
Cystic Fibrosis
and you are
between 13 and 20
years old
1
This is an early phase trial to determine
the dosage and safety of the new treatment.
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The purpose

This pilot study will be conducted in adolescents with cystic fibrosis (CF) without diabetes but with abnormal glucose tolerance, and will assess the effects of sitagliptin on glucose regulation. An oral glucose tolerance test (OGTT) and a mixed meal tolerance test (MMTT), will be performed at baseline and again ~4 weeks after treatment with study drug. We will also look at blood sugars throughout the day using a continuous glucose monitor (CGM) before each time the MMTT/OGTT are performed. Several hormones that may affect the way the body regulates blood sugars will be measured in blood when the OGTT and MMTT are done. We will assess the effect this medicine has on blood sugars (using CGM) and the effect the medicine has on the hormones measured during the OGTT and MMTT.

Provided treatments

  • Drug: Sitagliptin

Locations near you

Unfortunately, there are no recruiting locations near you. Please check the list with all locations below.
Tris trial is registered with FDA with number: NCT01721382. The sponsor of the trial is Nemours Children's Clinic and it is looking for 6 volunteers for the current phase.
Official trial title:
Treatment of Dysglycemia Using Sitagliptin in Adolescents With Cystic Fibrosis.