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You can access this
clinical trial
if you have
Chronic Obstructive Pulmonary Disease or Chronic Bronchitis
and you are
between 40 and 85
years old
Phase
-
The phase for this study is not defined.
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The purpose

N-acetylcysteine (NAC) is described as having mucolytic and antioxidant properties. It is widely prescribed for patients with chronic obstructive pulmonary disease (COPD), particularly for those who have accompanying symptoms of chronic cough and sputum production. Randomized, placebo controlled indicate that it is safe and that it may have some clinical benefit when used at relatively low doses. It is postulated that substantially higher doses of NAC will be well-tolerated and will provide better symptom control while also decreasing blood makers of oxidant stress and inflammation.

Provided treatments

  • Drug: N-acetylcysteine
  • Drug: Oral acetylcysteine
Tris trial is registered with FDA with number: NCT01599884. The sponsor of the trial is Minnesota Veterans Medical Research and Education Foundation and it is looking for 65 volunteers for the current phase.
Official trial title:
Effects of High-Dose N-Acetylcysteine on Respiratory Health Status in Patients With Chronic Obstructive Pulmonary Disease (COPD) and Chronic Bronchitis: A Randomized, Placebo-Controlled Trial-1