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More info
You can access this
clinical trial
if you have
Reflux Oesophagitis
and you are
between 18 and 45
years old
1
This is an early phase trial to determine
the dosage and safety of the new treatment.
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The purpose

The objectives of this study were: To compare repeated doses of YF476 at 2 dose levels, placebo and omeprazole with respect to their effect on basal- and food- stimulated gastric pH in healthy volunteers. To compare repeated doses of YF476 at 2 dose levels, placebo and omeprazole with respect to their effect on basal and meal stimulated pH. To assess the safety, tolerability and pharmacokinetics of repeated doses of YF476 in healthy volunteers.

Provided treatments

  • Drug: YF476
  • Drug: Omeprazole
Tris trial is registered with FDA with number: NCT01599858. The sponsor of the trial is Trio Medicines Ltd. and it is looking for 49 volunteers for the current phase.
Official trial title:
YF476: Effects of Repeated Dosing at 2 Dose Levels on 24-hour Ambulatory Gastric pH Compared With Placebo and Omeprazole in Healthy Volunteers