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Your journey
1What's a trial
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More info
You can access this
clinical trial
if you have
Complicated Urinary Tract Infection (cUTI) Including Acute Pyelonephritis
and you are
between 18 and 90
years old
This is a trial in the final phase before the treatment is released on the market.
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The purpose

The purpose of this study is to evaluate the effects of Ceftazidime Avibactam compared to Doripenem for treating hospitalized patients with complicated urinary tract infections, including acute pyelonephritis

Provided treatments

  • Drug: Ceftazidime - Avibactam ( CAZ-AVI)
  • Drug: Doripenem
  • Drug: Either switch to oral therapy: 500 mg of Ciprofloxacin (oral)
  • Drug: or switch to oral therapy: 800 mg/160 mg of sulfamethoxazole/trimethoprim (oral)

Locations near you

Unfortunately, there are no recruiting locations near you. Please check the list with all locations below.
Tris trial is registered with FDA with number: NCT01599806. The sponsor of the trial is Pfizer and it is looking for 641 volunteers for the current phase.
Official trial title:
A Phase III, Randomized, Multicenter, Double-Blind, Double Dummy, Parallel Group, Comparative Study to Determine the Efficacy, Safety, and Tolerability of Ceftazidime Avibactam (CAZ-AVI, Formerly CAZ104) Versus Doripenem Followed by Appropriate Oral Therapy in the Treatment of Complicated Urinary Tract Infections, Including Acute Pyelonephritis, With a Gram Negative Pathogen in Hospitalized Adults