This trial is withdrawn!
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You can access this
clinical trial
if you have
Non-Hodgkin's Lymphoma
and you are
over 18
years old
Phase
-
The phase for this study is not defined.
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The purpose

Rituximab is an antibody targeted against the CD20 antigen found primarily on B-cells. Therefore, an imaging agent targeting CD20 expression may provide a more accurate evaluation of extent of disease and response to therapy than the current standard of care, F-18 FDG PET/CT. The main purpose of the study is to investigate a new PET/CT imaging probe for detection and follow up of lymphoma. Following are the 3 aims of the study: a) Phase I testing in lymphoma patients of Cu-64 labelled Rituxan for defining normal tracer biodistribution, stability, pharmacokinetics and radiation dosimetry; b) comparison of Cu-64 Rituxan and F-18 FDG PET/CT in lymphoma patients; c) evaluation of changes in uptake of Cu-64 Rituxan in response to rituximab-based treatment in CD20-positive B-cell NHL

Provided treatments

  • Drug: Cu-64 Rituximab
Tris trial is registered with FDA with number: NCT01598558. The sponsor of the trial is Sanjiv Sam Gambhir and it is looking for 0 volunteers for the current phase.
Official trial title:
Assessing Response to Treatment in Non-Hodgkin's Lymphoma Patients Using 64Cu-DOTA-Rituximab PET/CT