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Your journey
1What's a trial
4Get in touch
More info
You can access this
clinical trial
if you have
Acute Leukemia, Chronic Leukemia, Myelodysplastic Syndrome or Non-Hodgkins Lymphoma
and you are
under 19
years old
The phase for this study is not defined.
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The purpose

Approximately 30% of patients who are candidates for bone marrow transplants do not have an HLA-matched, or close to matched, donor available. For this reason, doctors have been testing ways to make transplants from HLA-partially matched donors as safe and effective as transplants from HLA-matched donors. This study is being done to test the safety and the treatment results of a specific kind of transplant. In this transplant, blood from two donors will be used. Each donor will share one half of your HLA type. Blood from both donors will be transplanted at the same time.

Provided treatments

  • Radiation: total-body irradiation (TBI)
  • Drug: thiotepa
  • Drug: fludarabine phosphate
  • Drug: melphalan
  • Biological: anti-thymocyte globulin
  • Procedure: allogeneic hematopoietic stem cell transplantation
  • Biological: peripheral blood stem cell transplantation
  • Other: laboratory biomarker analysis

Locations near you

Unfortunately, there are no recruiting locations near you. Please check the list with all locations below.
Tris trial is registered with FDA with number: NCT01598025. The sponsor of the trial is Memorial Sloan Kettering Cancer Center and it is looking for 3 volunteers for the current phase.
Official trial title:
Biparental HLA Haplotype Disparate T-cell Depleted Transplants for Patients Lacking an HLACompatible Donor