The primary aim of this work is, to 'relate psychological and behavioural parameters of
hunger/satiety and food preference to gut hormones, neural activation and energy metabolism
by dietary manipulation, across the human lifespan'.
Other: Breakfast Study
Other: fMRI Study
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Locations near you
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Full eligibility criteria for NCT01597024
Ages eligible for Study
8 Years to 75 Years
Genders eligible for Study
Accepts Healthy Volunteers
Willingness to participate in the fMRI study
Not heavy smokers (less 10 day)
no metal in the body (including dental braces)
Heavy smokers (more than 10/day)
Morbid obese (BMI>40 kg/m2)
Obesity of known endocrine origin
Neurological disorders including Cerebral Palsy
Medication known to influence appetite (orlistat, oral antidiabetics, insulin, digoxin, anti-arrhythmics, sibutramine, antidepressants)
Self report fever/systemic infection
Inability to participate in fMRI scanning sessions including contraindications to MRI
Participation in medical or surgical weight loss programme within 1 month of selection
History of cerebrovascular disease
Current major depressive disorder, bipolar disorder or past history of suicide attempt or self harm
History of drug or alcohol misuse
History of significant cardiovascular disease
Allergy to any of the breakfasts components.
All locations for NCT01597024
University Medical Center Utrecht
Utrecht, Netherlands, 3584 CX
United Kingdom (1)
The Rowett Institute of Nutrition and Health, University of Aberdeen
Aberdeen, Aberdeenshire, United Kingdom, AB21 9SB
View full eligibility
Tris trial is registered with FDA with number: NCT01597024. The sponsor of the trial is University of Aberdeen and it is looking for 718 volunteers for the current phase.
Official trial title: Full4Health: Neuro-gut Interactions in Humans Across the Lifecourse
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