The Breathe Ventilator is a lightweight, wearable ventilator that has received U.S. FDA
clearance for use in patients with respiratory difficulty. The investigators believe that the
Breathe NIOV system will reduce the work of the diaphragm and breathing by providing added
tidal volume and oxygen. This will be a study in 14 patients with severe-to-very severe
chronic obstructive lung disease (COPD) to assess their work of breathing while using the
NIOV system as measured by esophageal and stomach pressures.