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Your journey
1What's a trial
2Find
3Review
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More info
You can access this
clinical trial
if you have
Prehypertension or Hypertension
and you are
between 45 and 65
years old
4
The primary goal of this phase is to monitor the long-term effects.
The treatment is already on the market.
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The purpose

The investigators hypothesize that nebivolol will improve endothelial t-PA release in adult humans with elevated blood pressure to a greater extent than either metoprolol or placebo. The investigators further hypothesize that the improvement in the capacity of the vascular endothelium to release t-PA with nebivolol is mediated, in part, by the compound's antioxidant properties.

Provided treatments

  • Drug: Nebivolol
  • Drug: Metoprolol
  • Drug: Placebo
  • Other: Bradykinin
  • Other: Saline
  • Other: Vitamin C

Locations near you

Unfortunately, there are no recruiting locations near you. Please check the list with all locations below.
Tris trial is registered with FDA with number: NCT01595516. The sponsor of the trial is University of Colorado, Boulder and it is looking for 44 volunteers for the current phase.
Official trial title:
Nebivolol and Endothelial Regulation of Fibrinolysis