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Your journey
1What's a trial
4Get in touch
More info
You can access this
clinical trial
if you have
Prehypertension or Hypertension
and you are
between 45 and 65
years old
The primary goal of this phase is to monitor the long-term effects.
The treatment is already on the market.
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The purpose

The investigators hypothesize that nebivolol will improve endothelial t-PA release in adult humans with elevated blood pressure to a greater extent than either metoprolol or placebo. The investigators further hypothesize that the improvement in the capacity of the vascular endothelium to release t-PA with nebivolol is mediated, in part, by the compound's antioxidant properties.

Provided treatments

  • Drug: Nebivolol
  • Drug: Metoprolol
  • Drug: Placebo
  • Other: Bradykinin
  • Other: Saline
  • Other: Vitamin C

Locations near you

Unfortunately, there are no recruiting locations near you. Please check the list with all locations below.
Tris trial is registered with FDA with number: NCT01595516. The sponsor of the trial is University of Colorado, Boulder and it is looking for 44 volunteers for the current phase.
Official trial title:
Nebivolol and Endothelial Regulation of Fibrinolysis